The Use of Bone Morphogenetic Protein in Lumbar SpineSurgery
by Jeffrey A. Rihn, Charley Gates, Steven D. Glassman, Frank M. Phillips, James D.Schwender, and Todd J. Albert
J Bone Joint Surg Am
Volume 90(9):2014-2025
September 1, 2008
©2008 by The Journal of Bone and Joint Surgery, Inc.
Axial (A), coronal (B), and sagittal (C) computed tomography images acquired twelve monthsafter an L4-L5 posterolateral fusion with use of rhBMP-2.
Jeffrey A. Rihn et al. J Bone Joint Surg Am 2008;90:2014-2025
©2008 by The Journal of Bone and Joint Surgery, Inc.
Jeffrey A. Rihn et al. J Bone Joint Surg Am 2008;90:2014-2025
©2008 by The Journal of Bone and Joint Surgery, Inc.
Jeffrey A. Rihn et al. J Bone Joint Surg Am 2008;90:2014-2025
©2008 by The Journal of Bone and Joint Surgery, Inc.
Jeffrey A. Rihn et al. J Bone Joint Surg Am 2008;90:2014-2025
©2008 by The Journal of Bone and Joint Surgery, Inc.
Jeffrey A. Rihn et al. J Bone Joint Surg Am 2008;90:2014-2025
©2008 by The Journal of Bone and Joint Surgery, Inc.
Jeffrey A. Rihn et al. J Bone Joint Surg Am 2008;90:2014-2025
©2008 by The Journal of Bone and Joint Surgery, Inc.
Intraoperative photograph demonstrating the approach for the transforaminal lumbar interbodyfusion.
Jeffrey A. Rihn et al. J Bone Joint Surg Am 2008;90:2014-2025
©2008 by The Journal of Bone and Joint Surgery, Inc.
After the disc space is prepared, the BMP-soaked collagen sponge is packed into the interbodycage, and the cage is inserted into the anterior two-thirds of the disc space to maximize lordosisand minimize the risk of exposing the nerve root to BMP.
Jeffrey A. Rihn et al. J Bone Joint Surg Am 2008;90:2014-2025
©2008 by The Journal of Bone and Joint Surgery, Inc.
Jeffrey A. Rihn et al. J Bone Joint Surg Am 2008;90:2014-2025
©2008 by The Journal of Bone and Joint Surgery, Inc.
Jeffrey A. Rihn et al. J Bone Joint Surg Am 2008;90:2014-2025
©2008 by The Journal of Bone and Joint Surgery, Inc.
Jeffrey A. Rihn et al. J Bone Joint Surg Am 2008;90:2014-2025
©2008 by The Journal of Bone and Joint Surgery, Inc.
Jeffrey A. Rihn et al. J Bone Joint Surg Am 2008;90:2014-2025
©2008 by The Journal of Bone and Joint Surgery, Inc.
Jeffrey A. Rihn et al. J Bone Joint Surg Am 2008;90:2014-2025
©2008 by The Journal of Bone and Joint Surgery, Inc.
Axial (A) and coronal (B) computed tomography scans demonstrating ectopic bone formation inthe intervertebral foramen (white arrows) following a transforaminal lumbar interbody fusionperformed with rhBMP-2.
Jeffrey A. Rihn et al. J Bone Joint Surg Am 2008;90:2014-2025
©2008 by The Journal of Bone and Joint Surgery, Inc.
Coronal computed tomography scan (A) and sagittal T1-weighted magnetic resonance image (B)demonstrating vertebral osteolysis six months following a transforaminal lumbar interbodyfusion performed with use of rhBMP-2.
Jeffrey A. Rihn et al. J Bone Joint Surg Am 2008;90:2014-2025
©2008 by The Journal of Bone and Joint Surgery, Inc.