CELL STRUCTURE
Jan Homolak, 2nd year
School of Medicine, Zagreb
4/28/2014
Mentor: A. Žmegač Horvat
The Cell
Discovery
The Cell
Theory
The Cell
Types
P
arts of
the Cell
Cella = small room
Cell Discovery
Robert Hooke
-
observed a thin slice of
cork (dead plant cells)
Microphagia
-
described what he
observed as “little
boxes” (cells)
1665
Anton van
Leeuwenhoek
first person to
observe living cells
1675
Cell Theory
ALL LIVING THINGS
ARE COMPOSED OF
basic units of
structure and function
come only from
existing cells
Matthias Schleiden (1838)
-
all plants are composed of cells
Theodor Schwann (1839)
-
all animals are composed of cells
Rudolph Virchow (1855)
-
cells come only from other cells
???
•
The largest cell in the human body?
•
The smallest cell in the human body?
•
The largest cell on earth?
•
The smallest cell?
•
which cell is the most abundant in the human
body?
There are more bacterial cells in the body than human cells.
the female ovum
male sperm
(175,000 sperm cells
weigh as much as a single egg cell)
an ostrich egg
a tiny bacteria
Eukaryotes vs. Prokaryotes
•
Animals
•
Plants
•
Fungi
•
Bacteria
true nucleus
Parts of the Cell
•
taking food
•
transforming food into energy
•
getting rid of wastes
•
reproducing
Cell Membrane
•
Structure:
-
phospholipid
bilayer
- proteins:
- channels
-
markers
-
receptors
•
Function: “selectively permeable boundary
between the cell and the external environment”
Nucleus
•
Structure: a sphere
•
Function:
-storage center of cell DNA
-manages cell functions
Cytoplasm
•
Structure:
- gelatin-like fluid
- inside the cell membrane
•
Function:
-contains salts, minerals
,
and organic
molecules
-surrounds the organelles
Cytoskeleton
•
Structure:
-network of thin, fibrous elements
microtubules
microfilaments (actin)
•
Function:
-support system
-maintains cell
shape
Ribosomes
•
Structure:
-two subunits made of protein and RNA
•
Function:
-protein synthesis
Endoplasmic Reticulum
•
Structure:
-a system of membranous tubules and sacs
•
Function:
-”intercellular highway”
r
ough
e
ndoplasmic
r
eticulum
s
mooth
e
ndoplasmic
r
eticulum
Rough Endoplasmic Reticulum
•
Covered with ribosomes
•
Protein synthesis and export
Smooth Endoplasmic Reticulum
•
Synthesis of lipids and breakdown of toxic
substances
Golgi Apparatus
•
Structure:
-stacked flat sacs
•
Function:
-distribution of
received proteins
(to other organelles or out of the cell)
(receiving, processing,
packaging, and shipping)
Mitochondria
•
Structure:
-folded membrane within an outer membrane
•
Function:
- energy conversion (food -> ATP)
Lysosomes
•
Structure:
-spherical organelles
•
Function:
-contain hydrolytic enzymes
Peroxisomes
•
Structure:
-spherical organelles
•
Function:
-degrade hydrogen peroxide
(toxic metabolic compound)
Centrioles
•
Structure:
-nine sets of triplet microtubules
-arranged in a ring
•
Function:
-cell division (mitosis)