CELL STRUCTURE
Jan Homolak, 2nd year
 School of Medicine, Zagreb 4/28/2014
Mentor: A. Žmegač Horvat
The CellDiscovery
The CellTheory
The CellTypesParts ofthe Cell
 Cella = small room
http://www.academyofwine.com/storage/articles/christine_cork/Cork%20Cells%20Magnified_400wide.jpg
Cell Discovery
Robert Hooke- observed a thin slice ofcork (dead plant cells)
Microphagia- described what heobserved as “littleboxes” (cells)
1665
https://lh4.googleusercontent.com/OHcksAWhBdwRoSSfcO-KFoRcUYxInS5EnXdnH5dscYXP7ALlOieEu0BlhiU-2G1E4RLVXPgwWeYLkJy3gMsX_zMwXAUbup56zV1oZH-RP-pYk-l3-ohOYf620A
http://static.bbc.co.uk/solarsystem/img/ic/640/scientists/robert_hooke/robert_hooke_large.jpg
http://upload.wikimedia.org/wikipedia/commons/thumb/1/17/Cork_Micrographia_Hooke.png/220px-Cork_Micrographia_Hooke.png
Anton vanLeeuwenhoek
first person toobserve living cells
1675
http://hzwms.dyndns.org/Structure_Function/lew_microscope.jpg
leeuwenhoek
Cell Theory
ALL LIVING THINGSARE COMPOSED OF 
http://3.bp.blogspot.com/-jT89WkLDld8/UELZ-hAORkI/AAAAAAAAPmY/NE_5Xhze60w/s1600/Animal-Cell.jpg
basic units ofstructure and function
come only fromexisting cells
Matthias Schleiden (1838)-all plants are composed of cells
Theodor Schwann (1839)all animals are composed of cells
Rudolph Virchow (1855)- cells come only from other cells
schleiden
schwann
rudolf_virchow
???
The largest cell in the human body? 
The smallest cell in the human body?
The largest cell on earth?
The smallest cell?
which cell is the most abundant in the humanbody?There are more bacterial cells in the body than human cells.
 the female ovum
male sperm (175,000 sperm cellsweigh as much as a single egg cell)
an ostrich egg
 a tiny bacteria
Eukaryotes vs. Prokaryotes
Animals
Plants
Fungi
Bacteria
http://www.bacterialphylogeny.com/img/eukaryotes/prokaryotes_eukaryotes.GIF
true nucleus
Parts of the Cell
taking food
transforming food into energy
getting rid of wastes
reproducing
Cell Membrane
Structure:- phospholipid   bilayer- proteins:- channels- markers- receptors
Function: “selectively permeable boundarybetween the cell and the external environment”
cellmemb
Nucleus
Structure: a sphere
Function:-storage center of cell DNA-manages cell functions
http://previewcf.turbosquid.com/Preview/2010/12/04__22_20_00/nucleus-c-01.jpgda249f91-073d-43a8-a224-cd4818a6a0e9Larger.jpg
http://www.wallpaperno.com/thumbnails/detail/20121102/star%20wars%20movies%20death%20star%201600x1200%20wallpaper_www.wallpaperno.com_88.jpg
Cytoplasm
Structure:- gelatin-like fluid- inside the cell membrane
Function:-contains salts, minerals, and organicmolecules
-surrounds the organelles
http://www.breast-cancer.ca/images/cytoplasm-illustration.jpg
Cytoskeleton
Structure:-network of thin, fibrous elementsmicrotubulesmicrofilaments (actin)
Function:-support system-maintains cell shape
Image115
Ribosomes
Structure:-two subunits made of protein and RNA
Function:-protein synthesis
ribosome
Endoplasmic Reticulum
Structure:-a system of membranous tubules and sacs
Function:-”intercellular highway”
rough endoplasmicreticulum
smooth endoplasmicreticulum
Rough Endoplasmic Reticulum
Covered with ribosomes
Protein synthesis and export
Smooth Endoplasmic Reticulum
Synthesis of lipids and breakdown of toxicsubstances
Golgi Apparatus
Structure:-stacked flat sacs
Function:-distribution of received proteins(to other organelles or out of the cell)
(receiving, processing,packaging, and shipping)
Mitochondria
Structure:-folded membrane within an outer membrane
Function:- energy conversion (food -> ATP)
Lysosomes
Structure:-spherical organelles
Function:-contain hydrolytic enzymes
Peroxisomes
Structure:-spherical organelles
Function:-degrade hydrogen peroxide(toxic metabolic compound)
peroxisomes
Centrioles
Structure:-nine sets of triplet microtubules-arranged in a ring
Function:-cell division (mitosis)
Untitled1